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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1A
All Species:
26.67
Human Site:
Y1315
Identified Species:
48.89
UniProt:
O95602
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95602
NP_056240.2
1720
194811
Y1315
K
Q
N
K
F
Q
V
Y
Q
L
R
F
Q
F
L
Chimpanzee
Pan troglodytes
XP_001135380
1723
195055
Y1315
K
Q
N
K
F
Q
V
Y
Q
L
R
F
Q
F
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532976
1699
192037
Y1297
K
Q
D
K
F
Q
V
Y
Q
L
R
F
Q
F
L
Cat
Felis silvestris
Mouse
Mus musculus
O35134
1717
194092
Y1322
K
R
N
K
F
Q
V
Y
E
L
R
F
Q
F
L
Rat
Rattus norvegicus
O54889
1716
194174
Y1322
K
Q
N
K
F
R
V
Y
E
L
R
F
Q
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL98
1390
155685
V1033
Q
M
E
P
G
S
A
V
G
A
L
C
A
Q
S
Frog
Xenopus laevis
NP_001082182
1730
195193
Y1320
K
S
Q
K
Y
Q
V
Y
K
I
R
F
H
F
L
Zebra Danio
Brachydanio rerio
XP_001922839
1693
190636
F1309
E
T
L
K
S
R
V
F
K
I
T
F
H
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91875
1642
185391
R1281
R
S
Y
E
Y
D
M
R
F
Q
F
L
P
R
E
Honey Bee
Apis mellifera
XP_001121092
1665
190473
Y1264
W
P
K
R
Q
L
I
Y
T
I
T
I
N
Y
L
Nematode Worm
Caenorhab. elegans
NP_001022450
1737
195064
R1349
D
I
L
A
A
E
K
R
E
L
G
A
R
H
L
Sea Urchin
Strong. purpuratus
XP_794863
1742
194988
Y1316
T
H
D
H
Y
R
V
Y
K
I
R
L
N
F
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P10964
1664
186413
N1300
H
M
R
F
F
D
N
N
E
Y
S
E
E
Y
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
N.A.
90
N.A.
86.8
87.9
N.A.
N.A.
27
68.1
67.9
N.A.
43.7
43.6
39.3
46.8
Protein Similarity:
100
99.1
N.A.
94.4
N.A.
93.3
93.8
N.A.
N.A.
43.9
81.7
81.3
N.A.
61.4
61.5
57.4
64.4
P-Site Identity:
100
100
N.A.
93.3
N.A.
86.6
86.6
N.A.
N.A.
0
60
33.3
N.A.
0
13.3
13.3
33.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
6.6
80
66.6
N.A.
26.6
40
33.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
38.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
56.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
8
0
0
8
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
8
0
16
0
0
16
0
0
0
0
0
0
0
0
8
% D
% Glu:
8
0
8
8
0
8
0
0
31
0
0
8
8
0
8
% E
% Phe:
0
0
0
8
47
0
0
8
8
0
8
54
0
62
0
% F
% Gly:
0
0
0
0
8
0
0
0
8
0
8
0
0
0
0
% G
% His:
8
8
0
8
0
0
0
0
0
0
0
0
16
8
0
% H
% Ile:
0
8
0
0
0
0
8
0
0
31
0
8
0
0
0
% I
% Lys:
47
0
8
54
0
0
8
0
24
0
0
0
0
0
0
% K
% Leu:
0
0
16
0
0
8
0
0
0
47
8
16
0
0
77
% L
% Met:
0
16
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
31
0
0
0
8
8
0
0
0
0
16
0
0
% N
% Pro:
0
8
0
8
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
8
31
8
0
8
39
0
0
24
8
0
0
39
8
0
% Q
% Arg:
8
8
8
8
0
24
0
16
0
0
54
0
8
8
0
% R
% Ser:
0
16
0
0
8
8
0
0
0
0
8
0
0
0
8
% S
% Thr:
8
8
0
0
0
0
0
0
8
0
16
0
0
0
0
% T
% Val:
0
0
0
0
0
0
62
8
0
0
0
0
0
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
24
0
0
62
0
8
0
0
0
16
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _